Applied Radiology
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Applications In Contrast Imaging
These supplements cover a variety of applications in CT and MR imaging and provide practical guidance to Radiologic Technologists and related healthcare professionals. To review a course, select the appropriate profession. To complete the post test and earn CE credits you must be registered and signed-in to appliedradiology.org.
Vueway™ (Gadopiclenol): Practical Considerations for Use
William Faulkner, BS,RT(R)(MR)(CT), FSMRT, MRSO (MRSC™)
Estimated time for completion: .75 hour   •   Date of Release: May 1, 2024   •   Expiration Date: April 30, 2027
Prior to 2023, six extracellular fluid magnetic resonance imaging (MRI) contrast agents were available in the US: ProHance® (gadoteridol), Gadavist® (gadobutrol), Dotarem® (gadoterate meglumine; Clariscan™ (gadoterate meglumine); Omniscan™ (gadodiamide); and MultiHance® (gadobenate dimeglumine). These gadolinium-based contrast agents (GBCAs) vary with respect to chelate structure (ionic vs nonionic; macrocyclic vs linear), molar concentration (the number of Gd molecules per mL), and relaxivity.
With decades of use, these agents were demonstrated to be quite safe; however, since 2006, concerns about the safety of GBCAs have come to light, particularly with regard to the less stable (linear, nonionic) agents. Specifically, nephrogenic systemic fibrosis (NSF) and Gd retention were seen more readily with the use of these less-stable agents. It became apparent that a macrocyclic, high-relaxivity GBCA would be ideal, optimizing patient safety without compromising image quality.
In 2023, the US Food and Drug Administration approved Vueway™ (gadopiclenol) injection, a macrocyclic, high relaxivity agent that represents a significant advancement in terms of efficacy and safety. This paper compares the properties, mechanism-of-action, dosing, efficacy, and safety of the currently available GBCAs to the new agent Vueway.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • Assess the properties, mechanism of action, and dosing of the available GBCAs;
  • Explain the differences in safety among the GBCAs;
  • Analyze the bases for the increased relaxivity of Vueway; and
  • Summarize the intraindividual clinical trial results of Vueway vs the comparators MultiHance and Gadavist.
Accreditation
This course is approved by The Association for Medical Imaging Management (AHRA) for 0.75 "Category A" ARRT continuing education credit.
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
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Modified Barium Swallow Study ACR-SPR Practice Parameter: 2023 Update
Jessica G. Zarzour, MD • Bonnie Martin-Harris, PhD  • Jeanne G. Hill, MD
Estimated time for completion: 1 hour   •   Date of release and review: March 1, 2024   •   Expiration Date: March 31, 2027
The modified barium swallow study (MBSS) is a videofluoroscopic imaging study used to evaluate oral and pharyngeal swallowing function and airway protection. The exam is typically performed by a radiologist together with a speech-language pathologist (SLP). The American College of Radiology (ACR) creates and periodically updates Practice Parameters and Technical Standards for various radiologic procedures, including the MBSS. The goal of these Practice Parameters is to “promote the safe and effective use of diagnostic and therapeutic radiology by describing specific training, skills, and techniques,” and to “narrow the variability among radiology practices and provide guidance to achieve quality in radiology.” In 2023, the ACR partnered with the Society of Pediatric Radiology (SPR) to update the MBSS Practice Parameter. The updated ACR-SPR Practice Parameter for the Performance of the Modified Barium Swallow Study is summarized herein.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • State the clinical benefits and indications for the modified barium swallow study (MBSS);
  • Detail the clinical benefit of standardized, validated protocols and commercially available barium sulfate products to reduce variability of the MBSS exam;
  • Describe the technical and patient considerations associated with the MBSS;
  • Implement the imaging protocol for a standardized MBSS examination;
  • Demonstrate opportunities for improved communication between radiologists and speech-language pathologists.
Disclosures
Jessica G. Zarzour, MD: Financial disclosures for Dr. Zarzour include: Consulting contract with Bracco Diagnostics, Inc.;
Honorarium for her participation in this monograph. She has no nonfinancial relationships to disclose.
Bonnie Martin-Harris: Financial disclosures for Dr. Martin-Harris include: Principal Investigator, NIH/NIDCD K23DC005764; Standardized assessment of swallowing impairment, 2003-2010; Principal Investigator, NIH/NIDCD 2K24DC012801-0, Data Science; Applications in Communication and Swallowing Disorders, 2013-2024; Clinical Impact of Respiratory- Swallow Training on Refractory Dysphagia in OP HNC, VA Merit Review Award 5101RX002352 2018-2022; Machine Vision Fellowship, Bracco Diagnostics, Inc. 2020-2021; MBSImP royalty recipient from the Medical University of South Carolina; Honorarium received from participation in this monograph.
Nonfinancial disclosure includes owner and license guarantor to Northern Speech Services (NSS).
Jeanne Hill, MD: Financial disclosure for Dr. Hill include: Honorarium for her participation in this monograph. She has no nonfinancial relationships to disclose.
Accreditation
This course is approved by The Association for Medical Imaging Management (AHRA) for 1.0 "Category A" ARRT continuing education credit.
ASHA Coninuting Education Logo
ASHA CE Provider approval does not imply endorsement of course content, specific products or clinical procedures.
This course is offered for 0.1 ASHA CEUs (Intermediate Level)
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
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Clinical Utility of Barium Sulfate Products: Formulation Determines Appropriate Use
Steven Sireci, MD
Estimated time for completion: .75 hour   •   Date of Release: June 14, 2021  •   Expiration Date: July 31, 2026
Barium-containing contrast media contain barium sulfate (BaSO4), as well as a number of additives. The BaSO4 provides radiodensity (ie, radio-opacity) and physical density (g/mL) to the suspension. Depending on the intended use of the contrast, the specific combination of additives provide other useful properties, including: BaSO4 particle suspension; mucosal coating; viscosity and texture; sweetness; filling and laxative effects; preservation; foaming prevention; and flavoring. Here we describe the purpose of each ingredient and additive found in BaSO4 contrast media products currently available for fluoroscopic and radiographic examinations. In addition, we review the role of these products in anatomic radiographic evaluation of the gastrointestinal (GI) tract and in evaluation of the physiology of swallowing. Finally, we review barium preparations used in computed tomography (CT) applications.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • Explain the role that BaSO4 plays in barium-containing contrast media;
  • Review the purpose of each ingredient/additive found in BaSO4 contrast media products available for fluoroscopic and radiographic examinations;
  • Describe the formulation of barium products that are appropriate for single- and double-contrast anatomic radiographic evaluation of the gastrointestinal (GI) tract;
  • Summarize qualities of the barium-containing contrast media used in evaluation of swallowing that make them most appropriate for that application; and,
  • State the properties of barium-containing contrast media used in computed tomography (CT) applications.
Accreditation
This course is approved by The Association for Medical Imaging Management (AHRA) for 0.75 "Category A" ARRT continuing education credit.
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
(Site Registration/Login Required)
Diagnosis and Management of Swallowing Physiology:
Standardized Contrast, the MBSImP & the IDDSI Framework
Catriona M. Steele, PhD, Bonnie Martin-Harris, PhD, Memorie Gosa, PhD, Stephanie Edwards Allen, BSRT, MBA
Estimated time for completion: 1 hour   •   Date of release and review: May 1, 2021   •   Expiration Date: May 31, 2026
The MBSS, also known as a video fluoroscopic swallow study (VFSS), is a barium-sulfate–enhanced fluoroscopic motion study used to evaluate anatomy and swallowing physiology si¬multaneously in real time. Varibar, an FDA-approved barium sulfate product for evaluation of dysphagia, together with The Modified Barium Swallow Impairment Profile (MBSImP), are used to ensure standardization and reproducibility in the MBSS. This monograph explains the relationship between Varibar, the MBSImP, and the International Dysphagia Diet Standardisation (IDDSI) framework in evaluation of swallowing in clinical practice.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • Explain how a standardized set of barium sulfate products is used during a modified barium swallow study (MBSS) to identify pathology related to swallowing physiology
  • Describe how the Modified Barium Swallow Impairment Profile (MBSImP) is used to ensure objective scoring and communication of the results of an MBSS
  • Review what the global International Dysphagia Diet Standardisation (IDDSI) framework is and how it is used to classify foods and liquids according to their physical properties (ie, consistency, stickiness, etc.)
  • Describe any pediatric-specific considerations related to use of the MBSS, MBSImP, and the IDDSI framework to assess and manage dysphagia in infants and children
  • Summarize best practices for assessing swallowing physiology using the MBSS in the clinical setting
Accreditation
This course is approved by The Association for Medical Imaging Management (AHRA) for 1.0 "Category A" ARRT continuing education credit.
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
(Site Registration/Login Required)
The Modified Barium Swallow Study: When, How, and Why?
Margaret M. Fynes, MD; Christine Smith, MS; and Martin B. Brodsky, PhD, ScM
Estimated time for completion: 1 hour   •   Date of Orignal Release: September 01, 2019  •   Updated Release: September 27, 2023  •   Expiration Date: September 30, 2026
Dysphagia is a common clinical challenge, particularly in the elderly. The modified barium swallow study (MBSS), initially developed by radiologists and speech-language pathologists (SLPs) at The Johns Hopkins Hospital, is critically important for evaluation and treatment of dysphagia. In this article, the authors, radiologist Margaret M. Fynes, MD, and two SLPs, Christine Smith, MS, and Martin B. Brodsky, PhD, ScM, review the technical and patient considerations for optimal performance of the MBSS according to The Johns Hopkins protocol. Because both perspectives, radiologist and SLP, are included, the article is able to highlight the importance of the role of each, as well as how they work together. Elements of the MBSS that have become more standardized over time, specifically the barium sulfate contrast agent products used, and the scoring and reporting of the examination with the Modified Barium Swallowing Impairment Profile (MBSImP), are described, and the contribution of this standardization to the overall accuracy and reliability of the MBSS is discussed.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • Review the causes and incidence of dysphagia
  • Describe technical and patient considerations associated with performing a fluoroscopic modified barium swallow study (MBSS) to evaluate dysphagia
  • Explain how the MBSS contributes to the evaluation and treatment of patients with dysphagia by assessing the cause of dysphagia and allowing implementation of compensatory strategies in real-time
  • Explain the importance of the relationship between the radiologist and speech-language pathologist (SLP) during performance of the MBSS
  • Explain how use of a standardized series of barium sulfate contrast agent products, as well as use of the Modified Barium Swallowing Impairment Profile (MBSImP), have contributed to standardization of the MBSS examination
  • Detail the benefits of MBSS standardization on the robustness and consistency of the examination
Accreditation
This course is approved by The Association for Medical Imaging Management (AHRA) for 1.0 "Category A" ARRT continuing education credit.
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
(Site Registration/Login Required)
Fluoroscopic Evaluation of the Bariatric Surgery Patient
Cheri Canon, MD, and Jayleen Grams, MD, PhD
Estimated time for completion: 1 hour   •   Date of Orignal Release: November 01, 2020  •   Updated Release: December 21, 2023  •   Expiration Date: December 31, 2026
Obesity has been linked to increases in several clinically significant comorbidities. To address these related health issues, the number of bariatric procedures is growing. This monograph describes the role Fluoroscopy plays in the evaluation of the bariatric patient including a review of the imaging protocols and their necessary findings; designed to guide clinical decisions regarding which bariatric procedure is most appropriate for the patient.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • Review the incidence of obesity and the role of bariatric surgery as a strategy to address it
  • Explain the advantages of fluoroscopy in the evaluation of the bariatric patient
  • Summarize the considerations when performing fluoroscopic evaluation of the pre- and post-operative bariatric patient
  • Describe the protocols for fluoroscopic imaging of the gastrointestinal (GI) tract, including single- and dual-phase esophagrams and upper GI examinations
  • Detail the main challenges to performing fluoroscopy in bariatric patients
  • Relate the value of communication between the radiologist and bariatric surgeon
Accreditation
This course is approved by The Association for Medical Imaging Management (AHRA) for 1.0 "Category A" ARRT continuing education credit.
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
(Site Registration/Login Required)
MRI Contrast Selection: Greater Stability or Higher Relaxivity?
Howard Rowley, MD, FACR; Lorna P. Browne, MD; Kevin J. Chang, MD, FACR; Christopher Comstock, MD, FACR; J. Paul Finn, MD; Scott Reeder, MD, PhD;
Max Wintermark, MD
Estimated time for completion: 1.0 hour   •   Date of Release: July 1, 2022  •   Expiration Date: June 30, 2024
Currently, 6 general-use gadolinium-based contrast agents (GBCA) are available and approved for a variety of MRI indications, including brain, body, and breast imaging, in adults and children. Gadolinium-based contrast agents comprise a gadolinium (Gd) ion bound to an organic ligand to form a chelate. Whether the chelate is linear or macrocyclic and ionic or nonionic impacts the size and stability of the Gd-chelate complex, as well as its distribution and elimination. In addition, the chelate structure also impacts the relaxivity, or r value, of the GBCA, which dictates the ability to provide contrast enhancement relative to background. Understanding the different safety and efficacy profiles of GBCAs can be valuable when selecting a GBCA. Here, we present discussions from a recent Expert Panel Forum focused on the safety and efficacy of GBCAs, as well as specific considerations related to their selection for neuroimaging, pediatric imaging, body imaging, and breast imaging applications.
Learning Objectives
At the conclusion of this activity, participants should be able to:
  • Describe the distinguishing properties of the available gadolinium-based contrast agents (GBCAs) currently used for magnetic resonance imaging (MRI);
  • Review how the structure of the gadolinium (Gd)-chelate complex determines the stability of a GBCA, and how stability relates to both Gd retention and nephrogenic systemic fibrosis (NSF);
  • Explain what a “high-relaxivity” GBCA is and summarize results of crossover studies comparing standard- and high-relaxivity GBCAs for MRI;
  • State the key considerations when selecting a GBCA for neuro MRI, pediatric MRI, body MRI, and breast MRI.
Accreditation
This course is approved by the The Association for Medical Imaging Management (AHRA) for 1.0 "Category A" ARRT continuing education credit.
Commercial Support
This program has been supported through an educational grant from Bracco Diagnostics, Inc.
To view and complete the Post-Exam and claim credits select Profession below.
(Site Registration/Login Required)